insulin resistance

noun

: reduced sensitivity to insulin by the body's insulin-dependent processes (such as glucose uptake and lipolysis) that is typical of type 2 diabetes but often occurs in the absence of diabetes

Examples of insulin resistance in a Sentence

Recent Examples on the Web
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Gary explained that disruptions in the endocrine system can trigger inflammation, leading to conditions like insulin resistance, polycystic ovary syndrome (PCOS), and autoimmune disorders, which are increasingly linked to cancer. Josh Hammer, Newsweek, 15 Feb. 2025 Weight gain Insulin can promote weight gain, so if it’s being produced in excess—as a result of consuming too much sugar, for example—that can lead to insulin resistance. Angela Altomare, Glamour, 14 Feb. 2025 However, supplementation can also cause side effects, such as insulin resistance. Merve Ceylan, Health, 12 Feb. 2025 Metabolic syndrome is related to insulin resistance and can harm the blood vessels. Katherine Hignett, Forbes, 3 Jan. 2025 See All Example Sentences for insulin resistance

Word History

First Known Use

1927, in the meaning defined above

Time Traveler
The first known use of insulin resistance was in 1927

Cite this Entry

“Insulin resistance.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/insulin%20resistance. Accessed 27 Feb. 2025.

Medical Definition

insulin resistance

noun
: reduced sensitivity to insulin by the body's insulin-dependent processes (as glucose uptake, lipolysis, and inhibition of glucose production by the liver) that results in decreased activity of these processes or an increase in insulin production or both and that is typical of type 2 diabetes but often occurs in the absence of diabetes
Last Updated: - Updated example sentences
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